SCHEMBL30977412

SCHEMBL30977412

FC(F)Oc1ccc2ccnn2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.36
GRIN1 Q05586 2/20 0.36
GRIN2B Q13224 2/20 0.36
DRD2 P14416 3/20 0.35
DRD4 P21917 3/20 0.35
DRD3 P35462 3/20 0.35
DRD1 P21728 2/20 0.35
HTR2A P28223 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
HSP90AA1 P07900 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
CCR6 P51684 1/20 0.35
ATM Q13315 1/20 0.35
SCN5A Q14524 2/20 0.35
F2RL3 Q96RI0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30977339 0.82 DRD2 (0.38) DRD2DRD4DRD3DRD1HTR2A
SCHEMBL18338474 0.76 DRD2 (0.45) DRD2DRD4DRD3DRD1HTR2A
SCHEMBL30977594 0.73 DRD2 (0.37) DRD2DRD4DRD3SLC6A2SLC6A4
SCHEMBL25421011 0.71 DRD2 (0.45) DRD2DRD4DRD3DRD1HTR2A
SCHEMBL30496653 0.71 DRD2 (0.43) DRD2DRD4DRD3DRD1HTR2A
SCHEMBL30175354 0.71 DRD2 (0.43) DRD2DRD4DRD3DRD1HTR2A
SCHEMBL4224982 0.69 SLC6A2 (0.36) DRD2DRD4DRD3DRD1HTR2A
SCHEMBL2316789 0.68 SCN5A (0.40) RXRAGRIN1GRIN2BDRD1MEN1
SCHEMBL31487889 0.68 MAOB (0.47) DRD2DRD4DRD3DRD1HTR2A
SCHEMBL24567001 0.68 DRD2 (0.54) DRD2DRD4DRD3DRD1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619402-A1 GPR17 MODULATORS AND USES THEREOF Myrobalan Therapeutics, Inc. (US) 2025-09-24 EP disclosed
CN-119613397-A N-heteroaromatic ring-3-sulfonamide compounds and use thereof for preparing GPR17 receptor inhibitors 迈巴制药(南京)有限公司 2025-03-14 CN disclosed
WO-2024104462-A1 GPR17 MODULATORS AND USES THEREOF MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) 2024-05-23 WO disclosed