Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30731672 | 0.82 | TNF (0.33) | KDRNPC1RAB9ATNFKDM4E | |
| SCHEMBL792707 | 0.76 | ADORA3 (0.44) | NPC1RAB9AFLT3HPGDKDM4E | |
| SCHEMBL17697692 | 0.75 | POLB (0.46) | PRMT5WDR77NPC1RAB9ATNF | |
| SCHEMBL11925488 | 0.72 | NPC1 (0.43) | KDRFGFR3PRMT5WDR77NPC1 | |
| SCHEMBL3030423 | 0.72 | KDR (0.41) | KDRFGFR3PRMT5WDR77NPC1 | |
| SCHEMBL557273 | 0.72 | KDR (0.41) | KDRFGFR3PRMT5WDR77NPC1 | |
| SCHEMBL30977530 | 0.71 | PIK3CA (0.37) | KDRFGFR3NPC1RAB9APIK3CA | |
| SCHEMBL25215804 | 0.70 | ALDH1A1 (0.35) | KDRFGFR3NPC1RAB9ATNF | |
| SCHEMBL16370092 | 0.70 | NPC1 (0.52) | KDRFGFR3PRMT5WDR77NPC1 | |
| SCHEMBL23103326 | 0.68 | KDR (0.40) | KDRFGFR3PRMT5WDR77NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619402-A1 | GPR17 MODULATORS AND USES THEREOF | Myrobalan Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-119613397-A | N-heteroaromatic ring-3-sulfonamide compounds and use thereof for preparing GPR17 receptor inhibitors | 迈巴制药(南京)有限公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2024104462-A1 | GPR17 MODULATORS AND USES THEREOF | MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) | 2024-05-23 | — | — | WO | disclosed |