Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PRUNE1 | Q86TP1 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26977759 | 0.88 | LMNA (0.40) | LMNAMAPTPIK3CAALDH1A1PRUNE1 | |
| SCHEMBL27036960 | 0.83 | LMNA (0.40) | LMNAMAPTPIK3CAALDH1A1PRUNE1 | |
| SCHEMBL26977745 | 0.83 | PRUNE1 (0.41) | LMNAMAPTPIK3CAALDH1A1PRUNE1 | |
| SCHEMBL26978014 | 0.82 | LMNA (0.42) | LMNAMAPTPIK3CAALDH1A1CYP2D6 | |
| SCHEMBL26977362 | 0.82 | LMNA (0.44) | LMNAMAPTPIK3CAALDH1A1PRUNE1 | |
| SCHEMBL26977718 | 0.81 | LMNA (0.43) | LMNAMAPTPIK3CAALDH1A1PRUNE1 | |
| SCHEMBL30977477 | 0.80 | PIK3CA (0.44) | LMNAMAPTPIK3CAALDH1A1PRUNE1 | |
| SCHEMBL26977735 | 0.79 | LMNA (0.48) | LMNAMAPTPIK3CAALDH1A1PRUNE1 | |
| SCHEMBL26978069 | 0.79 | LMNA (0.48) | LMNAMAPTPIK3CAALDH1A1PRUNE1 | |
| SCHEMBL12935065 | 0.79 | LMNA (0.48) | LMNAMAPTPIK3CAALDH1A1PRUNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619402-A1 | GPR17 MODULATORS AND USES THEREOF | Myrobalan Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-119613397-A | N-heteroaromatic ring-3-sulfonamide compounds and use thereof for preparing GPR17 receptor inhibitors | 迈巴制药(南京)有限公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2024104462-A1 | GPR17 MODULATORS AND USES THEREOF | MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) | 2024-05-23 | — | — | WO | disclosed |