Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PRUNE1 | Q86TP1 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30977515 | 0.87 | PRUNE1 (0.45) | PIK3CALMNAMAPTUSP2CYP1A2 | |
| SCHEMBL31736473 | 0.83 | LMNA (0.41) | PIK3CALMNAMAPTUSP2CYP1A2 | |
| SCHEMBL30977478 | 0.80 | LMNA (0.43) | PIK3CALMNAMAPTUSP2CYP1A2 | |
| SCHEMBL31736371 | 0.80 | MTNR1A (0.41) | PIK3CALMNAMAPTUSP2CYP1A2 | |
| SCHEMBL30977417 | 0.80 | USP2 (0.48) | PIK3CALMNAMAPTUSP2TSHR | |
| SCHEMBL31736504 | 0.78 | MAPT (0.42) | PIK3CALMNAMAPTUSP2TSHR | |
| SCHEMBL12935065 | 0.77 | LMNA (0.48) | PIK3CALMNAMAPTUSP2CYP1A2 | |
| SCHEMBL30977414 | 0.77 | LMNA (0.43) | PIK3CALMNAMAPTUSP2CYP1A2 | |
| SCHEMBL31025637 | 0.74 | LMNA (0.45) | PIK3CALMNAMAPTUSP2CYP1A2 | |
| SCHEMBL166618 | 0.72 | PIK3CA (0.56) | PIK3CALMNAMAPTUSP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619402-A1 | GPR17 MODULATORS AND USES THEREOF | Myrobalan Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-119613397-A | N-heteroaromatic ring-3-sulfonamide compounds and use thereof for preparing GPR17 receptor inhibitors | 迈巴制药(南京)有限公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2024104462-A1 | GPR17 MODULATORS AND USES THEREOF | MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) | 2024-05-23 | — | — | WO | disclosed |