SCHEMBL30977698

SCHEMBL30977698

CCCCCCCCC(CCCCCC)C(=O)OCCCCCC(CCCCCSCC(CCCCCC)OC(=O)CC1CCCCCC1)NCCCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 3/20 0.33
▸ ACHE P22303 2/20 0.33
▸ TLR2 O60603 2/20 0.31
▸ P2RY12 Q9H244 1/20 0.31
▸ PPARG P37231 3/20 0.31
▸ REN P00797 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ MMP1 P03956 1/20 0.30
▸ MMP3 P08254 1/20 0.30
▸ MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30977701 0.94 KLK7 (0.34) BCHEACHETLR2P2RY12PPARG
SCHEMBL30977728 0.91 BCHE (0.32) BCHEACHE
SCHEMBL30977717 0.90 KLK7 (0.37) BCHEACHETLR2PPARGTDP1
SCHEMBL30977707 0.90 KLK7 (0.37) BCHEACHETLR2PPARGTDP1
SCHEMBL31035789 0.89 TLR2 (0.38) TLR2
SCHEMBL30977742 0.89 KLK7 (0.36) BCHETLR2PPARGTDP1
SCHEMBL30977769 0.88 KLK7 (0.33) BCHEACHETLR2TDP1
SCHEMBL30977768 0.88 CHRM2 (0.32) BCHEACHEP2RY12PPARG
SCHEMBL30977733 0.87 TLR2 (0.37) TLR2
SCHEMBL30977766 0.86 CTSK (0.33) BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638417-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS Nanovation Therapeutics Inc. (CA) 2025-10-29 — — EP disclosed
US-20240398977-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-12-05 — — US disclosed
US-12121591-B2 Sulfur-containing ionizable lipids for the delivery of nucleic acids and other therapeutic agents NANOVATION THERAPEUTICS INC. (CA) 2024-10-22 — — US disclosed
US-20240261430-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-08-08 — — US disclosed
WO-2024130421-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-06-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12121591-B2 Sulfur-containing ionizable lipids for the delivery of nucleic acids and other therapeutic agents SLC43A1, NSUN3, NSUN2 BCHE 3833/4885ACHE 4820/4885TLR2 3615/4885
US-20240261430-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS SLC43A1, NSUN3, NSUN2 BCHE 3833/4885ACHE 4820/4885TLR2 3615/4885
US-20240398977-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS SLC43A1, NSUN3, NSUN2 BCHE 3833/4885ACHE 4820/4885TLR2 3615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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