Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097788 | 1.00 | KDM4E (0.52) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL2985752 | 0.89 | SMN1; SMN2 (0.58) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL2985756 | 0.89 | SMN1; SMN2 (0.58) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL3100866 | 0.88 | ALDH1A1 (0.46) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL2987309 | 0.80 | CDK4 (0.49) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL10384652 | 0.76 | MAPT (0.62) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL12222321 | 0.76 | SMN1; SMN2 (0.48) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL6428126 | 0.76 | SMN1; SMN2 (0.48) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL3103334 | 0.76 | MC5R (0.55) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL3103327 | 0.76 | MC5R (0.55) | KDM4EMAPTMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |