Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23662304 | 1.00 | GABRA1 (0.39) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL23662296 | 0.75 | BRD4 (0.52) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL23662233 | 0.75 | HTR2A (0.32) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL15825941 | 0.73 | BRD4 (0.47) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL15825879 | 0.72 | BRD4 (0.47) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL30977968 | 0.72 | BRD4 (0.55) | BRD4 | |
| SCHEMBL15825219 | 0.71 | BRD4 (0.44) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL15837318 | 0.71 | BRD4 (0.44) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL15825403 | 0.70 | BRD4 (0.45) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL15825251 | 0.69 | TP53 (0.36) | GABRA1GABRA5GABRA3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373809-A | Quinoxalinone compound and preparation method, pharmaceutical composition and application thereof | 徐州医科大学 | 2024-07-23 | — | — | CN | disclosed |