Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844299 | 0.92 | L3MBTL1 (0.41) | L3MBTL1KDM4EGAAHPGDMAOB | |
| SCHEMBL30602897 | 0.86 | L3MBTL1 (0.48) | L3MBTL1KDM4EGAAMAOBDYRK1A | |
| SCHEMBL29579957 | 0.85 | DYRK1A (0.37) | L3MBTL1KDM4EGAAHPGDMAOB | |
| SCHEMBL17826761 | 0.82 | L3MBTL1 (0.56) | L3MBTL1KDM4EGAAHPGDRAB9A | |
| SCHEMBL23817494 | 0.81 | TSHR (0.47) | KDM4EKMT2ATSHRALDH1A1 | |
| SCHEMBL27659861 | 0.77 | L3MBTL1 (0.44) | L3MBTL1KDM4EGAAHPGDDYRK1A | |
| SCHEMBL16800088 | 0.76 | TLR4 (0.33) | HPGDKMT2ATSHRALDH1A1 | |
| SCHEMBL3786544 | 0.75 | L3MBTL1 (0.58) | L3MBTL1KDM4EGAAHPGDRAB9A | |
| SCHEMBL16572858 | 0.75 | KDM4E (0.68) | L3MBTL1KDM4EGAAHPGDRAB9A | |
| SCHEMBL3786689 | 0.74 | L3MBTL1 (0.45) | L3MBTL1KDM4EGAAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684633-A | Androgen receptor modulators and methods of use thereof | 埃萨制药股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-113195441-B | Androgen receptor modulators and methods of use thereof | 埃萨制药股份有限公司 | 2024-07-12 | — | — | CN | disclosed |