SCHEMBL29844299

SCHEMBL29844299

CCCCOc1c(Cl)cccc1C#N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 4/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ SRC P12931 1/20 0.40
▸ TSHR P16473 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ HPGD P15428 3/20 0.38
▸ MAOB P27338 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.37
▸ KCNH2 Q12809 1/20 0.36
▸ AR P10275 1/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ CASP3 P42574 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ SENP8 Q96LD8 1/20 0.35
▸ SENP7 Q9BQF6 1/20 0.35
▸ SENP6 Q9GZR1 1/20 0.35
▸ LTA4H P09960 1/20 0.35
▸ DYRK1A Q13627 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30978112 0.92 L3MBTL1 (0.42) L3MBTL1KDM4ESRCTSHRGAA
SCHEMBL30602897 0.85 L3MBTL1 (0.48) L3MBTL1KDM4ESRCTSHRGAA
SCHEMBL29579957 0.83 DYRK1A (0.37) L3MBTL1KDM4ESRCGAAHPGD
SCHEMBL11233036 0.82 L3MBTL1 (0.54) L3MBTL1KDM4EGAAHPGDKCNH2
SCHEMBL1761182 0.81 TSHR (0.39) L3MBTL1KDM4ETSHRHPGDALDH1A1
SCHEMBL29844444 0.81 TSHR (0.39) L3MBTL1KDM4ETSHRHPGDALDH1A1
SCHEMBL29844274 0.77 AR (0.47) AR
SCHEMBL3787026 0.76 L3MBTL1 (0.57) L3MBTL1KDM4ETSHRGAAHPGD
SCHEMBL23356467 0.76 NPC1 (0.40) L3MBTL1KDM4ESRCTSHRGAA
SCHEMBL20414593 0.75 L3MBTL1 (0.51) L3MBTL1KDM4ETSHRHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617762-B2 Carboxy derivatives with antiinflamatory properties SITRYX THERAPEUTICS LIMITED (GB) 2026-05-05 — — US disclosed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 — — US disclosed
CN-115066418-A Carboxy derivatives with anti-inflammatory properties 西特瑞治疗有限公司 2022-09-16 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES CPA2, RO60, C5AR1 L3MBTL1 3425/4885KDM4E 1568/4885SRC 4647/4885
US-12617762-B2 Carboxy derivatives with antiinflamatory properties CCR1, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 L3MBTL1 599/4885KDM4E 3319/4885SRC 4097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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