Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30978112 | 0.85 | L3MBTL1 (0.42) | DYRK1AL3MBTL1KDM4EKMT2AGAA | |
| SCHEMBL29844299 | 0.83 | L3MBTL1 (0.41) | DYRK1AL3MBTL1KDM4EKMT2AGAA | |
| SCHEMBL21899044 | 0.81 | KMT2A (0.50) | L3MBTL1KDM4EKMT2AGAARAB9A | |
| SCHEMBL30602897 | 0.81 | L3MBTL1 (0.48) | DYRK1AL3MBTL1KDM4EKMT2AGAA | |
| SCHEMBL27659861 | 0.74 | L3MBTL1 (0.44) | DYRK1AL3MBTL1KDM4EGAASLC22A12 | |
| SCHEMBL24743717 | 0.73 | AR (0.34) | KDM4EKMT2AHPGDMAOBMEN1 | |
| SCHEMBL10461262 | 0.73 | KMT2A (0.50) | L3MBTL1KDM4EKMT2AGAARAB9A | |
| SCHEMBL28711958 | 0.73 | ALDH1A1 (0.54) | KDM4EKMT2AGAARAB9AHPGD | |
| SCHEMBL29579800 | 0.70 | AR (0.38) | RAB9AHPGDMAOBNPC1ALDH1A1 | |
| SCHEMBL24744295 | 0.70 | AR (0.33) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226349-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | ESSA PHARMA, INC. (CA) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022111526-A1 | BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |