Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601428 | 0.83 | MAT2A (0.48) | MAT2AMAPTHRH4SMN1; SMN2 | |
| SCHEMBL30979084 | 0.83 | TOP2A (0.43) | TOP2AMAT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL30979101 | 0.80 | TOP2A (0.37) | TOP2AMAT2AKDM4EMAPTHRH4 | |
| SCHEMBL29909120 | 0.79 | TOP2A (0.54) | TOP2AKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30979110 | 0.79 | TOP2A (0.39) | TOP2AMAT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL29909609 | 0.78 | KDM4E (0.37) | KDM4EMAPTHRH4ALDH1A1SMN1; SMN2 | |
| SCHEMBL23576802 | 0.78 | KDM4E (0.37) | KDM4EMAPTHRH4ALDH1A1SMN1; SMN2 | |
| SCHEMBL30979012 | 0.78 | HRH4 (0.43) | TOP2AKDM4EMAPTHRH4ALDH1A1 | |
| SCHEMBL30920847 | 0.77 | KDM4E (0.39) | TOP2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30961037 | 0.74 | SMN1; SMN2 (0.42) | TOP2AMAT2AKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |