Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30978935 | 0.83 | CYP1A1 (0.41) | CYP1A1CYP1A2CYP1B1KDM4EMAPT | |
| SCHEMBL30979084 | 0.81 | TOP2A (0.43) | TOP2AKDM4EMAPTTP53RXFP1 | |
| SCHEMBL30978994 | 0.79 | TOP2A (0.40) | TOP2AKDM4EMAPTMAT2AALDH1A1 | |
| SCHEMBL23601428 | 0.79 | MAT2A (0.48) | MAPTMAT2A | |
| SCHEMBL30979101 | 0.75 | TOP2A (0.37) | TOP2AKDM4EMAPTMAT2AALDH1A1 | |
| SCHEMBL29909120 | 0.75 | TOP2A (0.54) | TOP2AKDM4EMAPTTP53RXFP1 | |
| SCHEMBL29909000 | 0.74 | CYP1A1 (0.39) | CYP1A1CYP1A2CYP1B1MAPT | |
| SCHEMBL23577064 | 0.74 | CYP1A1 (0.39) | CYP1A1CYP1A2CYP1B1MAPT | |
| SCHEMBL30979012 | 0.73 | HRH4 (0.43) | TOP2ACYP1A2KDM4EMAPTALDH1A1 | |
| SCHEMBL30920847 | 0.72 | KDM4E (0.39) | TOP2AKDM4EMAPTTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |