Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 14/20 | 0.52 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979097 | 0.91 | ABCG2 (0.49) | ABCG2EGFRPOLBSMN1; SMN2PDE5A | |
| SCHEMBL30979063 | 0.86 | ABCG2 (0.52) | ABCG2POLBSMN1; SMN2PDE5AKMT2A | |
| SCHEMBL30979158 | 0.81 | KMT2A (0.46) | ABCG2EGFRPOLBSMN1; SMN2PDE5A | |
| SCHEMBL11702410 | 0.81 | L3MBTL1 (0.58) | POLBSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL30979013 | 0.80 | TP53 (0.43) | ABCG2EGFRPOLBPDE5AKMT2A | |
| SCHEMBL31169398 | 0.78 | ABCG2 (0.47) | ABCG2EGFRPDE5A | |
| SCHEMBL31169427 | 0.78 | TP53 (0.36) | EGFRPOLBPDE5AMAPT | |
| SCHEMBL30979069 | 0.77 | ALOX5 (0.45) | ABCG2EGFRPOLBKMT2AMEN1 | |
| SCHEMBL30979106 | 0.77 | LATS1 (0.43) | ABCG2POLBSMN1; SMN2PDE5AKMT2A | |
| SCHEMBL30979076 | 0.75 | EGFR (0.42) | ABCG2EGFRPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |