Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ECE1 | P42892 | 2/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988915 | 1.00 | HPGDS (0.39) | HPGDSFOLH1LMNACYP3A4NFKB1 | |
| SCHEMBL3094807 | 0.95 | LMNA (0.38) | HPGDSFOLH1LMNACYP3A4NFKB1 | |
| SCHEMBL3094812 | 0.95 | LMNA (0.38) | HPGDSFOLH1LMNACYP3A4NFKB1 | |
| SCHEMBL2987580 | 0.86 | FOLH1 (0.49) | FOLH1LMNACYP3A4NFKB1BLM | |
| SCHEMBL2987576 | 0.86 | FOLH1 (0.49) | FOLH1LMNACYP3A4NFKB1BLM | |
| SCHEMBL3095512 | 0.83 | LMNA (0.42) | HPGDSFOLH1LMNACYP3A4NFKB1 | |
| SCHEMBL3109216 | 0.83 | ANPEP (0.34) | ERAP2ANPEP | |
| SCHEMBL3091869 | 0.82 | CA12 (0.35) | FOLH1SIRT6SIRT1CA12CA1 | |
| SCHEMBL3095525 | 0.82 | FOLH1 (0.39) | FOLH1LMNACYP3A4NFKB1BLM | |
| SCHEMBL2979463 | 0.81 | FOLH1 (0.42) | FOLH1LMNACYP3A4NFKB1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |
| CN-101395164-A | N- (phosphonoalkyl) -amino acids, derivatives and compositions thereof, and methods of use | SCOTT EUGENE J VAN YU RUEY J (US) | 2009-03-25 | — | — | CN | claimed |
| CN-101395164-A | N- (phosphonoalkyl) -amino acids, derivatives and compositions thereof, and methods of use | SCOTT EUGENE J VAN YU RUEY J (US) | 2009-03-25 | — | — | CN | disclosed |