Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 4/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 3/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | BUB1 | O43683 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979671 | 1.00 | EPHA2 (0.47) | EPHA2P2RX3P2RX2ERBB2EPHB4 | |
| SCHEMBL12547063 | 0.83 | GPR119 (0.53) | HPGDSGPR119 | |
| SCHEMBL31690177 | 0.81 | MET (0.63) | — | |
| SCHEMBL22310758 | 0.80 | GPR119 (0.45) | HPGDSGPR119 | |
| SCHEMBL1552003 | 0.79 | EPHA2 (0.43) | EPHA2ERBB2EPHB4GPR119 | |
| SCHEMBL1552001 | 0.79 | EPHA2 (0.43) | EPHA2ERBB2EPHB4GPR119 | |
| SCHEMBL19474639 | 0.79 | EPHA2 (0.49) | EPHA2P2RX3P2RX2ERBB2EPHB4 | |
| SCHEMBL19474638 | 0.79 | EPHA2 (0.49) | EPHA2P2RX3P2RX2ERBB2EPHB4 | |
| SCHEMBL12547054 | 0.78 | HPGDS (0.48) | HPGDSGPR119 | |
| SCHEMBL31690168 | 0.78 | EPHX2 (0.47) | HPGDSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112120-A1 | DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |