Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588897 | 0.90 | MAPK10 (0.48) | POLBRAB9ANPC1PKMAKR1C3 | |
| SCHEMBL8303458 | 0.81 | DGAT1 (0.43) | RAB9ANPC1PKMKDM1AAKR1C3 | |
| SCHEMBL1997842 | 0.81 | F10 (0.61) | POLBRAB9ANPC1PKMMAPT | |
| SCHEMBL4414346 | 0.80 | DDB1 (0.43) | POLBRAB9ANPC1KDM1AGRM2 | |
| SCHEMBL15628295 | 0.78 | TNKS (0.40) | KDM1AAKR1C3MGLLALDH1A1 | |
| SCHEMBL29348768 | 0.78 | BCL2 (0.41) | KDM1AAKR1C3MGLLMEN1KMT2A | |
| SCHEMBL991958 | 0.78 | MEN1 (0.50) | RAB9ANPC1KDM1AMAPTMEN1 | |
| SCHEMBL30980982 | 0.77 | PIK3CA (0.44) | RAB9AMAPTMEN1KMT2ALMNA | |
| SCHEMBL5800891 | 0.77 | PIK3CA (0.43) | POLBMAPK10 | |
| SCHEMBL609306 | 0.75 | TP53 (0.59) | POLBNPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574189-B | EP300/CBP inhibitor | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |