Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303857 | 0.82 | TP53 (0.39) | PIK3CAMTORPDE10ALMNAALDH1A1 | |
| SCHEMBL29741392 | 0.79 | HPGD (0.63) | PDE10ALMNATSHRHPGDHTR2C | |
| SCHEMBL30980971 | 0.79 | KDM4E (0.40) | PIK3CAMTORTSHRHPGDALDH1A1 | |
| SCHEMBL8324767 | 0.79 | HPGD (0.63) | PDE10ALMNATSHRHPGDHTR2C | |
| SCHEMBL29741382 | 0.78 | LMNA (0.61) | PDE10ALMNATSHRHPGDHTR2C | |
| SCHEMBL30980945 | 0.77 | POLB (0.45) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL17151142 | 0.76 | PIK3CA (0.47) | PIK3CAMTORPDE10ALMNAHTR2C | |
| SCHEMBL12445267 | 0.75 | PIK3CA (0.46) | PIK3CAMTORPDE10ALMNAHTT | |
| SCHEMBL20180817 | 0.75 | PIK3CA (0.46) | PIK3CAMTORPDE10ALMNAHTR2C | |
| SCHEMBL15651208 | 0.73 | PIK3CA (0.47) | PIK3CAMTORPDE10ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574189-B | EP300/CBP inhibitor | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |