Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 4/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192199 | 0.91 | IDH1 (0.43) | TSHRSMN1; SMN2IDH1SCN9APARP1 | |
| SCHEMBL8303857 | 0.88 | TP53 (0.39) | KDM4EALDH1A1KMT2ASMN1; SMN2SCN9A | |
| SCHEMBL30980982 | 0.79 | PIK3CA (0.44) | KDM4EALDH1A1KMT2ATSHRPIK3CA | |
| SCHEMBL8256507 | 0.79 | SCN9A (0.43) | ALDH1A1SMN1; SMN2IDH1SCN9APARP1 | |
| SCHEMBL18630756 | 0.78 | MAPT (0.47) | KDM4EALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL8303458 | 0.78 | DGAT1 (0.43) | CMA1KDM1AF10 | |
| SCHEMBL8349969 | 0.76 | BPTF (0.43) | TSHRSCN9APARP1CMA1PIK3CA | |
| SCHEMBL4090586 | 0.75 | F10 (0.36) | ALDH1A1KMT2AHTR1AHTR1DHTR1B | |
| SCHEMBL15628295 | 0.74 | TNKS (0.40) | ALDH1A1CMA1KDM1AF10 | |
| SCHEMBL30980973 | 0.74 | PIK3CD (0.39) | HTR1AHTR1DHTR1BGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574189-B | EP300/CBP inhibitor | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |