SCHEMBL30980973

SCHEMBL30980973

O=C1OCCCN1c1cc(F)cc(F)c1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.39
PER2 O15055 1/20 0.37
CRY2 Q49AN0 1/20 0.37
ALOX5 P09917 1/20 0.37
KDM1A O60341 3/20 0.33
EGLN2 Q96KS0 1/20 0.33
F10 P00742 1/20 0.33
KCNQ2 O43526 1/20 0.33
BACE1 P56817 1/20 0.32
HTR1A P08908 1/20 0.32
HTR1D P28221 1/20 0.32
HTR1B P28222 1/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2B Q13224 2/20 0.32
TNKS O95271 1/20 0.32
HTR2C P28335 1/20 0.32
NAAA Q02083 1/20 0.32
CMA1 P23946 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30980936 0.90 DRD2 (0.40) PIK3CDPER2CRY2F10GRIN1
SCHEMBL4885970 0.80 EGLN2 (0.35) PER2CRY2ALOX5KDM1AEGLN2
SCHEMBL3587464 0.76 PSEN1 (0.38) EGLN2CMA1
SCHEMBL30980971 0.74 KDM4E (0.40) KDM1AF10KCNQ2HTR1AHTR1D
SCHEMBL8303857 0.74 TP53 (0.39) KDM1AHTR1AHTR1DHTR1BGRIN1
SCHEMBL991958 0.74 MEN1 (0.50) KDM1AHTR1AHTR1DHTR1BTNKS
SCHEMBL4414346 0.73 DDB1 (0.43) KDM1AF10TNKSCMA1
SCHEMBL4090586 0.72 F10 (0.36) PIK3CDKDM1AF10HTR1AHTR1D
SCHEMBL30669251 0.72 FADS1 (0.50) ALOX5KDM1ABACE1HTR2CNAAA
SCHEMBL17080008 0.72 LMNA (0.50) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574189-B EP300/CBP inhibitor 海创药业股份有限公司 2024-05-31 CN disclosed