Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741 | 0.88 | MAPT (0.55) | MAPTALDH1A1NPC1TNFRAB9A | |
| SCHEMBL27907 | 0.79 | MAPT (0.53) | MAPTALDH1A1NPC1TNFRAB9A | |
| SCHEMBL3125630 | 0.78 | FFAR1 (0.46) | MAPTALDH1A1NPC1TNFRAB9A | |
| SCHEMBL2391755 | 0.78 | ACHE (0.40) | MAPTALDH1A1NPC1TNFRAB9A | |
| SCHEMBL27875 | 0.78 | MAPT (0.51) | MAPTALDH1A1NPC1TNFRAB9A | |
| SCHEMBL18280129 | 0.76 | RECQL (0.49) | MAPTALDH1A1RAB9APAX8HTT | |
| SCHEMBL23983756 | 0.75 | CRBN (0.43) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL18280038 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1RAB9AHTTLMNA | |
| SCHEMBL197968 | 0.73 | ACHE (0.57) | ALDH1A1RAB9AACHEHSD17B10BCHE | |
| SCHEMBL27906 | 0.73 | MAPT (0.54) | MAPTALDH1A1NPC1TNFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652161-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | Uppthera, Inc. (KR) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155112-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | UPPTHERA, INC. (KR) | 2024-07-25 | — | — | WO | disclosed |