Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.63 |
| ▸ | RXRB | P28702 | 2/20 | 0.63 |
| ▸ | RXRG | P48443 | 2/20 | 0.63 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.62 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | KMO | O15229 | 1/20 | 0.59 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.53 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15011761 | 1.00 | RXRA (0.63) | RXRARXRBRXRGLPAR1LPAR5 | |
| SCHEMBL2708209 | 0.87 | SRD5A2 (0.71) | RXRARXRBRXRGSRD5A2AKR1C3 | |
| SCHEMBL10996319 | 0.86 | NAAA (0.56) | RXRARXRBRXRGLPAR1LPAR5 | |
| SCHEMBL19612714 | 0.86 | NAAA (0.56) | RXRARXRBRXRGLPAR1LPAR5 | |
| Hydrochloric Acid SCHEMBL2710358 | 0.85 | SRD5A2 (0.69) | RXRARXRBRXRGSRD5A2AKR1C3 | |
| Hydrochloric Acid SCHEMBL2710360 | 0.85 | SRD5A2 (0.69) | RXRARXRBRXRGSRD5A2AKR1C3 | |
| SCHEMBL2775115 | 0.85 | MAPT (0.63) | RXRARXRBRXRGLPAR1LPAR5 | |
| SCHEMBL70012 | 0.84 | AKR1C3 (0.85) | SRD5A2AKR1C3KMOMRGPRX4PARP15 | |
| SCHEMBL16429240 | 0.84 | AKR1C3 (0.85) | SRD5A2AKR1C3KMOMRGPRX4PARP15 | |
| SCHEMBL30307447 | 0.84 | AKR1C3 (0.85) | SRD5A2AKR1C3KMOMRGPRX4PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317947-A | Sortilin inhibitors | 索蒂纳制药股份有限公司 | 2024-07-09 | — | — | CN | disclosed |