Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PDE8A | O60658 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983894 | 0.78 | DAPK1 (0.65) | HTTSCN9ADAPK1HPGDFLT4 | |
| SCHEMBL30983811 | 0.74 | DAPK1 (0.62) | HTTSCN9ADAPK1HPGDFLT4 | |
| SCHEMBL30983919 | 0.74 | DAPK1 (0.47) | MEN1HTTRECQLKMT2ANPSR1 | |
| SCHEMBL31269215 | 0.74 | KCNH2 (0.34) | MEN1HTTRECQLKMT2ANPSR1 | |
| SCHEMBL30983779 | 0.74 | KCNH2 (0.36) | SCN9AKCNH2SCN5APIK3CD | |
| SCHEMBL30983829 | 0.74 | KCNH2 (0.34) | SCN9AKCNH2SCN5APIK3CDPDE10A | |
| SCHEMBL31269114 | 0.72 | DAPK1 (0.60) | HTTSCN9ADAPK1HPGDFLT4 | |
| SCHEMBL30984045 | 0.72 | DAPK1 (0.43) | MEN1HTTRECQLKMT2ANPSR1 | |
| SCHEMBL31269054 | 0.72 | KCNH2 (0.34) | SCN9AKCNH2SCN5APIK3CDPDE10A | |
| SCHEMBL30983905 | 0.68 | HDAC1 (0.45) | MEN1KMT2ASCN9AKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |