Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAPK1 | P53355 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983894 | 0.85 | DAPK1 (0.65) | DAPK1HPGDHRH4ADORA2API4KA | |
| SCHEMBL30983811 | 0.81 | DAPK1 (0.62) | DAPK1HPGDHRH4ADORA2API4KA | |
| SCHEMBL30984045 | 0.81 | DAPK1 (0.43) | DAPK1HPGDCYP19A1MEN1HTT | |
| SCHEMBL31269114 | 0.79 | DAPK1 (0.60) | DAPK1HPGDHRH4ADORA2API4KA | |
| SCHEMBL30983852 | 0.74 | MEN1 (0.42) | DAPK1HPGDHRH4PDE10AMEN1 | |
| SCHEMBL31269049 | 0.69 | GPR119 (0.37) | NSD2 | |
| 9-Benzyl-6-Methoxy-9H-Purine SCHEMBL28939425 | 0.67 | HPGD (0.77) | DAPK1HPGDHRH4ADORA2API4KA | |
| SCHEMBL822916 | 0.65 | YTHDC1 (0.57) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL22533420 | 0.65 | HPGD (0.56) | DAPK1HPGDADORA2API4KAPI4K2B | |
| SCHEMBL29424867 | 0.65 | HPGD (0.56) | DAPK1HPGDADORA2API4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |