Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983926 | 0.90 | ADORA3 (0.35) | CNR1KCNH2ADORA3CNR2MEN1 | |
| SCHEMBL30983813 | 0.86 | PDCD1 (0.34) | CNR1ADORA3CNR2MC4RMEN1 | |
| SCHEMBL30983814 | 0.86 | PDCD1 (0.34) | CNR1ADORA3CNR2MC4RMEN1 | |
| SCHEMBL30983809 | 0.85 | TLR7 (0.38) | CNR1KCNH2TLR7CNR2MC4R | |
| SCHEMBL30984067 | 0.84 | CNR1 (0.40) | CNR1KCNH2TLR7SLC6A4KDM4E | |
| SCHEMBL30983784 | 0.84 | PIK3CD (0.40) | CNR1CNR2MEN1KMT2ASLC6A4 | |
| SCHEMBL30983843 | 0.83 | PDCD1 (0.36) | CNR1ADORA3CNR2MEN1KMT2A | |
| SCHEMBL31269147 | 0.83 | CTSA (0.33) | CNR1ADORA3PIK3CD | |
| SCHEMBL31321974 | 0.82 | CTSA (0.32) | CNR1ADORA3KMT2APIK3CD | |
| SCHEMBL30983829 | 0.82 | KCNH2 (0.34) | CNR1KCNH2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |