Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | HTR1D | P28221 | 4/20 | 0.38 |
| ▸ | HTR1B | P28222 | 4/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31269160 | 0.99 | HTR1A (0.37) | HTR1AHTR1DHTR1BPIK3CDHTR6 | |
| SCHEMBL30983363 | 0.87 | HTR1D (0.40) | HTR1AHTR1DHTR1BPIK3CDHTR6 | |
| SCHEMBL30983408 | 0.87 | DRD2 (0.36) | HTR1AHTR1DHTR1BPIK3CDHTR6 | |
| SCHEMBL30983530 | 0.87 | PDE2A (0.38) | HTR1AHTR1DHTR1BPIK3CDHTR6 | |
| SCHEMBL30983572 | 0.86 | HTR6 (0.40) | HTR1AHTR1DHTR1BPIK3CDHTR6 | |
| SCHEMBL30983453 | 0.86 | PIK3CD (0.39) | HTR1AHTR1DHTR1BPIK3CDHTR6 | |
| SCHEMBL30983989 | 0.85 | PIK3CD (0.42) | HTR1AHTR1DHTR1BPIK3CD | |
| SCHEMBL30983438 | 0.85 | KIT (0.35) | HTR1AHTR1DHTR1BPIK3CDHTR6 | |
| SCHEMBL30983515 | 0.85 | KIT (0.41) | HTR1AHTR1DHTR1BPIK3CDHTR6 | |
| SCHEMBL30983795 | 0.84 | PDE2A (0.42) | PIK3CDHTR6LTA4HDRD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |