Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 5/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984784 | 0.86 | DDB1 (0.45) | GPR119DDB1CRBNNAMPTCCNC | |
| SCHEMBL1558660 | 0.85 | DDB1 (0.52) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL31306767 | 0.84 | ALDH1A1 (0.47) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL30955791 | 0.81 | DDB1 (0.49) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL9951949 | 0.81 | DDB1 (0.49) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL30955756 | 0.81 | DDB1 (0.49) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL23612193 | 0.80 | DDB1 (0.51) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL25904916 | 0.80 | GPR119 (0.40) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL18383140 | 0.79 | ALDH1A1 (0.46) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL15192197 | 0.79 | ALDH1A1 (0.46) | GPR119DDB1CRBNALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |