Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | NAMPT | P43490 | 4/20 | 0.42 |
| ▸ | ACACB | O00763 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035020 | 0.89 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTDDB1CRBN | |
| SCHEMBL1558660 | 0.86 | DDB1 (0.52) | ALDH1A1LMNAMAPTDDB1CRBN | |
| SCHEMBL30984829 | 0.84 | GPR119 (0.45) | ALDH1A1LMNAMAPTDDB1CRBN | |
| SCHEMBL16423801 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTDDB1CRBN | |
| SCHEMBL31306762 | 0.83 | DDB1 (0.45) | DDB1CRBNGPR119NAMPTACACB | |
| SCHEMBL26981235 | 0.83 | DDB1 (0.45) | DDB1CRBNGPR119NAMPTACACB | |
| SCHEMBL14662465 | 0.83 | DDB1 (0.45) | DDB1CRBNGPR119NAMPTACACB | |
| SCHEMBL30955791 | 0.82 | DDB1 (0.49) | ALDH1A1LMNAMAPTDDB1CRBN | |
| SCHEMBL22587586 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTDDB1CRBN | |
| SCHEMBL30955756 | 0.82 | DDB1 (0.49) | ALDH1A1LMNAMAPTDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431366-A | IRAK4 degradation agent compound and application thereof | 江苏先声药业有限公司 | 2025-02-14 | — | — | CN | disclosed |