Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25583436 | 0.93 | SOS1 (0.44) | SOS1CRBNGPR119PDE4APDE4B | |
| SCHEMBL31677307 | 0.91 | SOS1 (0.44) | SOS1CRBNMLKLPDE4APDE4B | |
| SCHEMBL30864059 | 0.91 | SOS1 (0.44) | SOS1CRBNMLKLPDE4APDE4B | |
| SCHEMBL27123605 | 0.90 | SOS1 (0.43) | SOS1CRBNGPR119FFAR4DDB1 | |
| SCHEMBL30148829 | 0.90 | CRBN (0.42) | SOS1CRBNMLKLPDE4APDE4B | |
| SCHEMBL31255654 | 0.89 | SOS1 (0.43) | SOS1CRBNGPR119PDE4APDE4B | |
| SCHEMBL30816879 | 0.88 | SOS1 (0.50) | SOS1CRBNMLKLFFAR4NR3C1 | |
| SCHEMBL31677366 | 0.87 | SOS1 (0.48) | SOS1CRBNMLKLKCNH2ALDH1A1 | |
| SCHEMBL27117256 | 0.87 | SOS1 (0.56) | SOS1CRBNMLKLFFAR4NR3C1 | |
| SCHEMBL24735127 | 0.86 | CRBN (0.47) | CRBNPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |