Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25583436 | 0.95 | SOS1 (0.44) | SOS1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30278930 | 0.95 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DBACE1 | |
| Trifluoroacetic Acid SCHEMBL31255415 | 0.92 | SOS1 (0.43) | SOS1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31255261 | 0.89 | CRBN (0.43) | SOS1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31255281 | 0.89 | SOS1 (0.44) | SOS1ALDH1A1KDM4E | |
| SCHEMBL30984835 | 0.89 | SOS1 (0.51) | SOS1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31255680 | 0.88 | HDAC4 (0.42) | PDE4APDE4BPDE4CPDE4DCRBN | |
| SCHEMBL24735127 | 0.87 | CRBN (0.47) | PDE4APDE4BPDE4CPDE4DCRBN | |
| SCHEMBL30158207 | 0.87 | CRBN (0.47) | PDE4APDE4BPDE4CPDE4DCRBN | |
| SCHEMBL21409304 | 0.86 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4DCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720044-A1 | AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD | Beactica Therapeutics AB (SE) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024240840-A1 | AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD | BEACTICA THERAPEUTICS AB (SE) | 2024-11-28 | — | — | WO | disclosed |