Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.44 |
| ▸ | ATXN2 | Q99700 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31677203 | 0.91 | ENPP2 (0.45) | SOS1ENPP2ATXN2ALDH1A1CYP2D6 | |
| SCHEMBL31677226 | 0.91 | ENPP2 (0.45) | SOS1ENPP2ATXN2ALDH1A1CYP2D6 | |
| SCHEMBL31677251 | 0.91 | SOS1 (0.44) | SOS1ENPP2ATXN2CYP2D6ACACB | |
| SCHEMBL31677315 | 0.90 | ENPP2 (0.45) | SOS1ENPP2ATXN2CYP2D6ACACB | |
| SCHEMBL30984835 | 0.87 | SOS1 (0.51) | SOS1ALDH1A1CYP2D6POLBCYP2C19 | |
| SCHEMBL30816879 | 0.85 | SOS1 (0.50) | SOS1CYP2D6TSHRMLKLCRBN | |
| SCHEMBL31677297 | 0.84 | ENPP2 (0.44) | SOS1ENPP2ATXN2ALDH1A1CYP2D6 | |
| SCHEMBL27117256 | 0.84 | SOS1 (0.56) | SOS1ALDH1A1CYP2D6TSHRMEN1 | |
| SCHEMBL30864007 | 0.81 | SOS1 (0.46) | SOS1CYP2D6TSHRMLKLCRBN | |
| SCHEMBL30864035 | 0.81 | CHRM2 (0.48) | ALDH1A1CYP2D6TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4631942-A1 | PAN-KRAS DEGRADING AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-10-15 | — | — | EP | disclosed |
| EP-4606803-A1 | KRAS G12D DEGRADATION AGENT, AND PREPARATION METHOD AND USE THEREFOR | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-08-27 | — | — | EP | disclosed |