Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24437313 | 1.00 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL27809732 | 0.88 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL22500809 | 0.86 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7418335 | 0.82 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL29019304 | 0.81 | ALDH1A1 (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL1530500 | 0.81 | GRIA2 (0.44) | PDE4APDE4BPDE4CPDE4DCA12 | |
| SCHEMBL24437033 | 0.79 | CCR2 (0.45) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL22517016 | 0.78 | HDAC1 (0.55) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL584842 | 0.77 | GRIA2 (0.47) | PDE4APDE4BPDE4CPDE4DCA12 | |
| SCHEMBL24437149 | 0.77 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113660932-B | Phenyl derivatives having pendant alkyl and alkenyl extensions and pharmaceutical compositions comprising the same | 景凯生物科技股份有限公司 | 2024-07-12 | — | — | CN | disclosed |