Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.44 |
| ▸ | GSK3A | P49840 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723359 | 0.77 | BRAF (0.34) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL31723386 | 0.75 | CDK1 (0.32) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL29440625 | 0.70 | SMN1; SMN2 (0.41) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL22807312 | 0.70 | SMN1; SMN2 (0.41) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL31186586 | 0.70 | SMN1; SMN2 (0.41) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL29701183 | 0.70 | CDK1 (0.39) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL29969954 | 0.70 | BRAF (0.42) | BRAFL3MBTL1 | |
| SCHEMBL30987326 | 0.68 | BRAF (0.36) | BRAF | |
| SCHEMBL24879123 | 0.67 | BRAF (0.46) | TSHRALDH1A1KDM4ENPC1GAA | |
| SCHEMBL31723352 | 0.67 | BRAF (0.38) | CDK1CCNB1GSK3AGSK3BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024147703-A1 | SHP2 INHIBITOR AND USES THEREOF | 주식회사 카나프테라퓨틱스 | 2024-07-11 | — | — | WO | disclosed |