Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.32 |
| ▸ | GSK3A | P49840 | 4/20 | 0.32 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723359 | 0.86 | BRAF (0.34) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL30987339 | 0.75 | CDK1 (0.44) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL31723357 | 0.74 | TNF (0.36) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL29969954 | 0.71 | BRAF (0.42) | BRAF | |
| SCHEMBL30987326 | 0.69 | BRAF (0.36) | BRAF | |
| SCHEMBL24879123 | 0.68 | BRAF (0.46) | BRAF | |
| SCHEMBL31723352 | 0.68 | BRAF (0.38) | CDK1CCNB1GSK3AGSK3BBRAF | |
| SCHEMBL24878852 | 0.64 | ESR2 (0.50) | BRAF | |
| SCHEMBL22832007 | 0.64 | GSK3A (0.48) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL24879033 | 0.63 | CLK1 (0.48) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |