Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723379 | 0.81 | MCL1 (0.56) | TNFMCL1HDAC6P2RX3DDR1 | |
| SCHEMBL12933340 | 0.68 | MCL1 (0.57) | MCL1DDR1LMNA | |
| SCHEMBL31723355 | 0.68 | BRAF (0.36) | TNF | |
| SCHEMBL31723357 | 0.68 | TNF (0.36) | TNFMCL1DDR1LMNA | |
| SCHEMBL30987296 | 0.67 | HSD17B13 (0.41) | — | |
| SCHEMBL30987319 | 0.66 | MCL1 (0.58) | TNFMCL1DDR1LMNA | |
| SCHEMBL12933333 | 0.65 | HDAC6 (0.65) | PDE5ATNFHDAC6P2RX3 | |
| SCHEMBL13820349 | 0.64 | MCL1 (0.56) | TNFMCL1DDR1LMNA | |
| SCHEMBL12160614 | 0.64 | L3MBTL1 (0.56) | PDE5A | |
| SCHEMBL18026639 | 0.64 | SMN1; SMN2 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024147703-A1 | SHP2 INHIBITOR AND USES THEREOF | 주식회사 카나프테라퓨틱스 | 2024-07-11 | — | — | WO | disclosed |