Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562932 | 0.77 | KDM4E (0.44) | ALDH1A1MAPK1MAPTLMNAHSD17B10 | |
| SCHEMBL458419 | 0.73 | NPC1 (0.46) | ALDH1A1NPC1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL6560797 | 0.73 | AVPR2 (0.48) | ALDH1A1NPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL30987383 | 0.72 | NPC1 (0.51) | ALDH1A1NPC1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL2396469 | 0.70 | CYP11B1 (0.44) | ALDH1A1NPC1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL15879736 | 0.69 | ALDH1A1 (1.00) | ALDH1A1NPC1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL17279827 | 0.69 | GRM5 (0.48) | ALDH1A1NPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL6450076 | 0.68 | GRM5 (0.65) | ALDH1A1NPC1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL25113195 | 0.68 | GRM5 (0.36) | ALDH1A1NPC1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL30987381 | 0.68 | BCHE (0.62) | ALDH1A1NPC1MAPK1LMNANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | disclosed |