Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | LDHA | P00338 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987377 | 0.88 | MIF (0.55) | BCHENOTUMMIFCA12CA1 | |
| SCHEMBL25055359 | 0.88 | MIF (0.74) | BCHENOTUMMIFCA12CA1 | |
| SCHEMBL30987390 | 0.88 | MIF (0.55) | BCHENOTUMMIFCA12CA1 | |
| SCHEMBL30987376 | 0.86 | CA2 (0.51) | BCHENOTUMMIFCA12CA1 | |
| SCHEMBL30987379 | 0.86 | NOTUM (0.50) | BCHENOTUMMIFCA12CA1 | |
| SCHEMBL30987393 | 0.84 | ABCG2 (0.57) | BCHENOTUMMIFCA12CA1 | |
| SCHEMBL12821585 | 0.84 | NOTUM (0.48) | BCHENOTUMMIFCA12CA1 | |
| SCHEMBL3270459 | 0.84 | NOTUM (0.57) | BCHENOTUMMIFCA12CA1 | |
| SCHEMBL30987400 | 0.82 | STIM1 (0.52) | BCHENOTUMMIFCA12CA1 | |
| SCHEMBL30987380 | 0.79 | NOTUM (0.52) | BCHENOTUMMIFCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | claimed |
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | disclosed |