Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GGH | Q92820 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105927 | 0.88 | GABRP (0.36) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3098894 | 0.82 | CPB2 (0.33) | CYP1A2PPARDTSHRMEN1GAA | |
| SCHEMBL3087485 | 0.81 | GSR (0.37) | CYP1A2PPARDMEN1KMT2A | |
| SCHEMBL3100745 | 0.77 | CA12 (0.36) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL2991467 | 0.77 | FOLH1 (0.50) | FOLH1CYP1A2GGHGRM3NAALAD2 | |
| SCHEMBL2991471 | 0.77 | FOLH1 (0.50) | FOLH1CYP1A2GGHGRM3NAALAD2 | |
| SCHEMBL3103459 | 0.75 | CA12 (0.35) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL4655463 | 0.75 | CYP1A2 (0.45) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7701636 | 0.75 | CYP1A2 (0.45) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3102609 | 0.74 | CA12 (0.37) | FOLH1MEN1GAACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |