Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 3/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.38 |
| ▸ | CHRNG | P07510 | 2/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.38 |
| ▸ | CHRND | Q07001 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30297062 | 0.96 | HTT (0.41) | HTTFURINCHRNA1CHRNGCHRNB1 | |
| SCHEMBL30988364 | 0.93 | FURIN (0.42) | HTTFURINSIRT1SMN1; SMN2SIRT2 | |
| SCHEMBL25787504 | 0.90 | FURIN (0.40) | HTTFURINCHRNA1CHRNGCHRNB1 | |
| SCHEMBL15699736 | 0.90 | FURIN (0.40) | HTTFURINCHRNA1CHRNGCHRNB1 | |
| SCHEMBL22138596 | 0.89 | FURIN (0.39) | HTTFURINCHRNA1CHRNGCHRNB1 | |
| SCHEMBL20705515 | 0.89 | FURIN (0.39) | HTTFURINCHRNA1CHRNGCHRNB1 | |
| SCHEMBL19681567 | 0.89 | FURIN (0.39) | HTTFURINCHRNA1CHRNGCHRNB1 | |
| SCHEMBL27447192 | 0.89 | FURIN (0.39) | HTTFURINCHRNA1CHRNGCHRNB1 | |
| SCHEMBL25831637 | 0.89 | HTT (0.41) | HTTFURINCHRNA1CHRNGCHRNB1 | |
| SCHEMBL23355149 | 0.88 | CTSL (0.42) | HTTFURINSIRT1SIRT2NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955604-A | Steroid compounds and antibody conjugates thereof | 里珍纳龙药品有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-112004557-B | Steroid compounds and antibody conjugates thereof | 里珍纳龙药品有限公司 | 2024-07-30 | — | — | CN | disclosed |