Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46774 | 0.97 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| SCHEMBL3092846 | 0.95 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| SCHEMBL26612129 | 0.95 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| Water SCHEMBL5420438 | 0.95 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| Hydrochloric Acid SCHEMBL641317 | 0.95 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| SCHEMBL12633292 | 0.89 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| Sulfuric Acid SCHEMBL28174949 | 0.89 | ALDH1A1 (0.49) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| Tert-Butylamine SCHEMBL27942385 | 0.87 | LMNA (0.50) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| SCHEMBL16002978 | 0.85 | HTT (0.55) | ALDH1A1LMNAHPGDHSD17B10TSHR | |
| SCHEMBL3091613 | 0.85 | ALDH1A1 (0.64) | ALDH1A1LMNAKDM4EUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110312730-B | Cytotoxins and conjugates, uses thereof and methods of preparation | 四川科伦博泰生物医药股份有限公司 | 2024-06-18 | — | — | CN | disclosed |