Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46774 | 0.97 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| Water SCHEMBL5420438 | 0.95 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| SCHEMBL26612129 | 0.95 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| Hydrochloric Acid SCHEMBL641317 | 0.95 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| Iodide SCHEMBL30988366 | 0.95 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| SCHEMBL12633292 | 0.89 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| Sulfuric Acid SCHEMBL28174949 | 0.89 | ALDH1A1 (0.49) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| Tert-Butylamine SCHEMBL27942385 | 0.87 | LMNA (0.50) | ALDH1A1LMNAKDM4EUSP2HPGD | |
| SCHEMBL16002978 | 0.85 | HTT (0.55) | ALDH1A1LMNAHPGDHSD17B10TSHR | |
| SCHEMBL3091613 | 0.85 | ALDH1A1 (0.64) | ALDH1A1LMNAKDM4EUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076302-B2 | Pyrimidine nucleoside derivatives and salts thereof | ARIGEN PHARMACEUTICALS, INC. (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20100234405-A1 | PYRIMIDINE NUCLEOSIDE DERIVATIVES AND SALTS THEREOF | ARIGEN PHARMACEUTICALS, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234405-A1 | PYRIMIDINE NUCLEOSIDE DERIVATIVES AND SALTS THEREOF | PNP, TYMP, NUDT1 | ALDH1A1 1134/4885LMNA 2164/4885KDM4E 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.