Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 7/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256777 | 0.88 | GLA (0.59) | GLALMNAALDH1A1THRBTSHR | |
| SCHEMBL30988943 | 0.86 | GLA (0.59) | GLALMNAALDH1A1THRBTSHR | |
| SCHEMBL4272926 | 0.82 | CA2 (0.60) | GLALMNAALDH1A1THRBTSHR | |
| SCHEMBL6353718 | 0.81 | AKR1C2 (0.51) | GLALMNAALDH1A1MAPK1EGFR | |
| Metronidazole SCHEMBL366212 | 0.81 | LMNA (0.75) | GLALMNAALDH1A1THRBTSHR | |
| SCHEMBL3777224 | 0.81 | EGFR (0.70) | GLAALDH1A1EGFRERBB2MAPT | |
| SCHEMBL16151836 | 0.80 | GLA (0.78) | GLALMNAALDH1A1THRBTSHR | |
| SCHEMBL1667860 | 0.79 | ALDH1A1 (0.60) | GLAALDH1A1EGFRERBB2MAPT | |
| Metronidazole Benzoate SCHEMBL366213 | 0.79 | GLA (0.68) | GLAALDH1A1EGFRERBB2MAPT | |
| SCHEMBL26231954 | 0.79 | GLA (0.68) | GLALMNAALDH1A1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344384-A | Compounds and uses thereof | 丹诺医药(苏州）有限公司 | 2024-07-16 | — | — | CN | disclosed |