Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MDM4 | O15151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401049 | 0.93 | CASP3 (0.60) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL29401389 | 0.90 | CASP3 (0.61) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL28641187 | 0.90 | CASP3 (0.61) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL29400163 | 0.90 | CASP3 (0.61) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL13163900 | 0.90 | CASP3 (0.61) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL29907904 | 0.89 | CASP3 (0.55) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL30919288 | 0.88 | KMT2A (0.54) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL7163160 | 0.88 | CASP3 (0.61) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL13382806 | 0.88 | CASP3 (0.61) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL29738269 | 0.88 | MDM4 (0.50) | CASP3KMT2AMDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097744-A2 | DNA-COMPATIBLE WITTIG OLEFINATION OF ON-DNA PEPTIDYL-YLIDES FOR DEVELOPMENT OF ON-DNA PEPTIDOMIMETICS THROUGH DIVERSITY-ORIENTED SYNTHESIS (DOS) | THE ROCKEFELLER UNIVERSITY (US) | 2024-05-10 | — | — | WO | disclosed |