Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.55 |
| ▸ | TLR2 | O60603 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713440 | 0.89 | TLR2 (0.57) | CASP3TLR2KMT2AMDM2TNF | |
| SCHEMBL30434908 | 0.89 | TLR2 (0.57) | CASP3TLR2KMT2AMDM2TNF | |
| SCHEMBL31091386 | 0.89 | TLR2 (0.51) | CASP3TLR2KMT2ATNFMDM4 | |
| SCHEMBL30988972 | 0.89 | CASP3 (0.59) | CASP3KMT2AMDM2MDM4TP53 | |
| SCHEMBL29401049 | 0.89 | CASP3 (0.60) | CASP3KMT2AMDM2MDM4TP53 | |
| SCHEMBL5452734 | 0.88 | CASP3 (0.56) | CASP3TLR2KMT2AMDM2 | |
| SCHEMBL16327986 | 0.88 | TLR2 (0.59) | TLR2MDM2TNF | |
| SCHEMBL30229906 | 0.88 | TLR2 (0.51) | CASP3TLR2KMT2ATNFMDM4 | |
| SCHEMBL13163900 | 0.86 | CASP3 (0.61) | CASP3KMT2AMDM2MDM4TP53 | |
| SCHEMBL28641187 | 0.86 | CASP3 (0.61) | CASP3KMT2AMDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022186782-A1 | METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Nγ-HYDROXY- OR Nγ-AMINO-L-ASPARAGINE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2022-09-09 | — | — | WO | disclosed |