Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 4/20 | 0.39 |
| ▸ | JAK3 | P52333 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25233792 | 1.00 | NUDT1 (0.54) | NUDT1TSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL30989273 | 0.86 | KDM4E (0.43) | NUDT1TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL25211367 | 0.86 | KDM4E (0.43) | NUDT1TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL30989297 | 0.84 | NUDT1 (0.54) | NUDT1TSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL25222245 | 0.84 | NUDT1 (0.54) | NUDT1TSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL25242164 | 0.82 | NUDT1 (0.52) | NUDT1TSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL30424316 | 0.82 | NUDT1 (0.52) | NUDT1TSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL29266900 | 0.78 | KDM4E (0.39) | TSHRKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL14759956 | 0.76 | ALDH1A1 (0.41) | KMT2AALDH1A1MEN1KDM4ELMNA | |
| SCHEMBL29904835 | 0.76 | ALDH1A1 (0.41) | KMT2AALDH1A1MEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302411-A | Therapeutic indazole compounds and methods of use thereof for the treatment of cancer | 基因泰克公司 | 2024-07-05 | — | — | CN | disclosed |