SCHEMBL30989419

SCHEMBL30989419

O=Cc1c(O)cccc1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 6/20 0.52
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
MAOB P27338 2/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
NFE2L2 Q16236 2/20 0.39
PADI4 Q9UM07 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL913980 1.00 ERN1 (0.52) ERN1TRIM24TRIM33MAOBABCG2
SCHEMBL95708 0.83 ERN1 (0.50) ERN1ABCG2KMT2AMEN1ALDH1A1
SCHEMBL311198 0.83 ERN1 (0.54) ERN1TRIM24TRIM33KMT2AMEN1
SCHEMBL27847569 0.82 ERN1 (0.42) ERN1MAOBABCG2KMT2AALDH1A1
SCHEMBL30522433 0.80 ERN1 (0.52) ERN1TRIM24TRIM33KMT2AMEN1
SCHEMBL29220003 0.80 ERN1 (0.52) ERN1TRIM24TRIM33KMT2AMEN1
SCHEMBL30541650 0.80 ERN1 (0.52) ERN1TRIM24TRIM33KMT2AMEN1
Charcoal, Activated SCHEMBL29407959 0.80 ERN1 (0.52) ERN1TRIM24TRIM33KMT2AMEN1
SCHEMBL31074946 0.79 CDK4 (0.50) ERN1MAOBABCG2KMT2AALDH1A1
SCHEMBL28436573 0.79 CDK4 (0.50) ERN1MAOBABCG2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665712-A1 COMPOUNDS, THEIR COMPOSITION AND THEIR USE AS NEMATICIDES Bhukhanwala, Komal (IN) 2025-12-24 EP disclosed
WO-2024171229-A1 COMPOUNDS, THEIR COMPOSITION AND THEIR USE AS NEMATICIDES BHUKHANWALA KOMAL (IN) 2024-08-22 WO disclosed
CN-118359638-A Compound serving as RET kinase inhibitor and preparation method and application thereof 苏州朗睿生物医药有限公司 2024-07-19 CN disclosed