SCHEMBL913980

SCHEMBL913980

O=Cc1c(O)cccc1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 6/20 0.52
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
MAOB P27338 2/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
NFE2L2 Q16236 2/20 0.39
PADI4 Q9UM07 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30989419 1.00 ERN1 (0.52) ERN1TRIM24TRIM33MAOBABCG2
SCHEMBL95708 0.83 ERN1 (0.50) ERN1ABCG2KMT2AMEN1ALDH1A1
SCHEMBL311198 0.83 ERN1 (0.54) ERN1TRIM24TRIM33KMT2AMEN1
SCHEMBL27847569 0.82 ERN1 (0.42) ERN1MAOBABCG2KMT2AALDH1A1
SCHEMBL30522433 0.80 ERN1 (0.52) ERN1TRIM24TRIM33KMT2AMEN1
SCHEMBL29220003 0.80 ERN1 (0.52) ERN1TRIM24TRIM33KMT2AMEN1
SCHEMBL30541650 0.80 ERN1 (0.52) ERN1TRIM24TRIM33KMT2AMEN1
Charcoal, Activated SCHEMBL29407959 0.80 ERN1 (0.52) ERN1TRIM24TRIM33KMT2AMEN1
SCHEMBL31074946 0.79 CDK4 (0.50) ERN1MAOBABCG2KMT2AALDH1A1
SCHEMBL28436573 0.79 CDK4 (0.50) ERN1MAOBABCG2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118754872-A 2-Alkenyl indole compound and preparation method and application thereof 周口师范学院 2024-10-11 CN claimed
CN-117209741-A Preparation method of Schiff base catalyst and preparation method of polyglycolic acid 中国科学院长春应用化学研究所 2023-12-12 CN claimed
CN-114933764-B Luminous high-performance PVC optical cable material and preparation method thereof 宁波格亿达光缆科技有限公司 2023-07-21 CN claimed
CN-116239460-A Continuous process for converting olefins and carbon dioxide to acrylic acid salts by means of a solution phase reactor 切弗朗菲利浦化学公司 2023-06-09 CN claimed
US-11530177-B2 Formation of α,β-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-12-20 US claimed
CN-114933764-A Luminous high-performance PVC optical cable material and preparation method thereof 宁波格亿达光缆科技有限公司 2022-08-23 CN claimed
CN-113201233-B Photochromic organic pigment and preparation method thereof 宁波中苑颜料有限公司 2022-07-01 CN claimed
EP-3638645-B1 CONTINUOUS PROCESS FOR THE CONVERSION OF OLEFINS AND CARBON DIOXIDE TO ACRYLATES VIA SOLUTION PHASE REACTOR CHEVRON PHILLIPS CHEMICAL CO LP (US) 2021-11-24 EP claimed
CN-113201233-A Photochromic organic pigment and preparation method thereof 宁波中苑颜料有限公司 2021-08-03 CN claimed
US-20210179525-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2021-06-17 US claimed
EP-3390337-A2 FORMATION OF ALFA, BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES Chevron Phillips Chemical Company LP (US) 2018-10-24 EP claimed
CN-108368017-A α -unsaturated carboxylic acids and salts thereof formed from metallolactones and anionic polyelectrolytes 切弗朗菲利浦化学公司 2018-08-03 CN claimed
US-20170166506-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-06-15 US claimed
CN-1200017-C Nickel compound catalyst system for polymerization of norbornene and its prepn CHINESE ACAD INST CHEMISTRY (CN) 2005-05-04 CN claimed
CN-1167720-C Polymeric catalyst system of norbornaene and its preparing process 中国科学院化学研究所 2004-09-22 CN claimed
CN-1139606-C Norbornene catalytic system and its preparation method and application 中国科学院化学研究所 2004-02-25 CN claimed
CN-1394685-A Norbornene catalytic system and its preparation method and application CHINESE ACAD INST CHEMISTRY (CN) 2003-02-05 CN claimed
CN-1390867-A Polymeric catalyst system of norbornaene and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2003-01-15 CN claimed
CN-1388140-A Nickel compound catalyst system for polymerization of norbornene and its prepn CHINESE ACAD INST CHEMISTRY (CN) 2003-01-01 CN claimed
CN-1388139-A Norbornene polymerization catalyst system and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2003-01-01 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170166506-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES DEGS1, ALOX12, ALOX15 ERN1 2639/4885TRIM24 631/4885TRIM33 2211/4885
US-20210179525-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES ME1, DEGS1, ACSL1 ERN1 3043/4885TRIM24 882/4885TRIM33 1937/4885
US-11530177-B2 Formation of α,β-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes ME1, ACSL1, ALOX12 ERN1 3032/4885TRIM24 721/4885TRIM33 1728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.