SCHEMBL95708

SCHEMBL95708

O=Cc1c(F)cccc1F

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
ALDH1A1 P00352 1/20 0.48
NFE2L2 Q16236 3/20 0.46
IKBKB O14920 1/20 0.43
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
ABCG2 Q9UNQ0 1/20 0.39
PKM P14618 1/20 0.38
PKLR P30613 1/20 0.38
KCNH2 Q12809 2/20 0.38
MAT2A P31153 1/20 0.38
BCHE P06276 1/20 0.37
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL652253 0.85 ERN1 (0.59) ERN1MEN1KMT2ATDP1ALDH1A1
SCHEMBL8702525 0.84 ERN1 (0.53) ERN1MEN1KMT2ATDP1ALDH1A1
SCHEMBL30989419 0.83 ERN1 (0.52) ERN1MEN1KMT2ATDP1ALDH1A1
SCHEMBL1695346 0.83 ERN1 (0.42) ERN1MEN1KMT2ATDP1ALDH1A1
SCHEMBL829563 0.83 ERN1 (0.42) ERN1MEN1KMT2ATDP1ALDH1A1
SCHEMBL31227003 0.83 ACHE (0.48) ERN1MEN1KMT2ATDP1ALDH1A1
SCHEMBL62458 0.83 MAOB (0.46) ERN1MEN1KMT2ATDP1ALDH1A1
SCHEMBL913980 0.83 ERN1 (0.52) ERN1MEN1KMT2ATDP1ALDH1A1
SCHEMBL1663012 0.83 ACHE (0.48) ERN1MEN1KMT2ATDP1ALDH1A1
SCHEMBL31057535 0.83 MAOB (0.46) ERN1MEN1KMT2ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2313 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136656-A Method for synthesizing diaryl methane compound in large quantity and application thereof 山东理工大学 2025-06-13 CN claimed
CN-120040469-A Preparation method of rui Lu Geli and intermediate thereof 齐鲁制药有限公司 2025-05-27 CN claimed
CN-119306568-A Synthesis method of 2, 6-difluorostyrene 山东京博农化科技股份有限公司 2025-01-14 CN claimed
CN-117143598-B High-entropy carbon quantum dot nanomaterial and preparation method and application thereof 中南大学 2024-11-08 CN claimed
CN-118496215-A Polyhydroxylated onium derivative with disubstituted benzene ring, preparation method and medical application thereof 中国药科大学 2024-08-16 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-117903168-A Pyrrolo [2,3-d ] thiazole derivatives, and preparation method and application thereof 南开大学 2024-04-19 CN claimed
CN-117624148-A Polyhydroxy sulfonium salt derivative with disubstituted benzene ring, preparation method and medical application thereof 中国药科大学 2024-03-01 CN claimed
EP-0660832-B1 SEROTONIN RECEPTOR AGENTS MERRELL PHARMA INC (US) 1998-01-14 EP claimed
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
EP-0560268-B1 Substituted pipecolinic acid derivatives as HIV protease inhibitors BIO MEGA BOEHRINGER INGELHEIM (CA) 1995-01-04 EP claimed
EP-0560268-A1 Substituted pipecolinic acid derivatives as HIV protease inhibitors BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP claimed
EP-0323637-B1 L(-) 2,6-DIFLUOROBENZOIC-N-(1,1,1-TRIFLUORO-PROP-2-YL)AMIDE BAYER AG (DE) 1992-12-16 EP claimed
EP-0281186-B1 PROCESS FOR THE PREPARATION OF A BENZOIC ACID DERIVATIVE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-10-28 EP claimed
EP-0189960-B1 NOVEL INSECTICIDAL 1,3-THIAZOLE DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-04-24 EP claimed
EP-0271923-B1 N-(2,6-difluorobenzoyl)-N'-3-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy) ethoxy] phenyl urea having insecticidal activity ISTITUTO GUIDO DONEGANI S.p.A. (IT) 1990-08-22 EP claimed
EP-0323637-A1 L(-) 2,6-difluorobenzoic-N-(1,1,1-trifluoro-prop-2-yl)amide BAYER AG (DE) 1989-07-12 EP claimed
EP-0088343-B1 UREA DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1985-07-03 EP claimed