Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31041031 | 0.75 | PIN1 (0.41) | MPOMAPK14MAOBHTTALOX5 | |
| SCHEMBL30699478 | 0.74 | KDM1A (0.40) | SMN1; SMN2MAOBHTTKDM1AALOX5 | |
| SCHEMBL29071014 | 0.72 | PIN1 (0.41) | MPOMAPK14MAOBHTT | |
| SCHEMBL24663897 | 0.71 | — | — | |
| SCHEMBL2888867 | 0.69 | KDM1A (0.45) | SMN1; SMN2RAB9AMAPK14MAOBKDM1A | |
| SCHEMBL25164958 | 0.68 | PTGES (0.40) | MPOMAPK14MAOBALOX5 | |
| SCHEMBL27381121 | 0.68 | PIN1 (0.40) | SMN1; SMN2RAB9AMPOMAPK14STAT3 | |
| SCHEMBL25165363 | 0.68 | PIN1 (0.40) | MPOMAPK14MAOBNFKB1DCPS | |
| SCHEMBL15280466 | 0.67 | ELANE (0.45) | SMN1; SMN2MAPK14STAT3HTTKDM1A | |
| SCHEMBL20521874 | 0.67 | KDM1A (0.48) | SMN1; SMN2RAB9AMAOBNPC1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307563-A | Polycyclic compound and preparation method and application thereof | 四川汇宇制药股份有限公司 | 2024-07-09 | — | — | CN | disclosed |