Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112864 | 0.86 | ALOX15 (0.51) | ALOX15KDM4ELMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2952907 | 0.84 | ALOX15 (0.56) | ALOX15KDM4ELMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27687311 | 0.84 | ALOX15 (0.56) | ALOX15KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL28051808 | 0.84 | SMN1; SMN2 (0.62) | ALOX15KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL18083916 | 0.84 | HDAC6 (0.60) | KDM4EALDH1A1GAAMAPTHDAC6 | |
| SCHEMBL3250190 | 0.83 | MAPT (0.59) | ALOX15KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2648559 | 0.82 | ALDH1A1 (0.58) | ALOX15KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31442962 | 0.82 | ALDH1A1 (0.58) | ALOX15KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5270854 | 0.82 | CA2 (0.60) | SMN1; SMN2ALDH1A1MAPTTHRBMEN1 | |
| SCHEMBL5924414 | 0.82 | CA2 (0.60) | SMN1; SMN2ALDH1A1MAPTTHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803822-B2 | Triazole derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20090105253-A1 | Triazole Derivative and Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |
| EP-0141377-B1 | METAL COMPLEXES | HODOGAYA CHEMICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |
| US-4563409-A | ELECTROGRAPHY | HOGOHAYA CHEMICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| EP-0141377-A2 | Metal complexes | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105253-A1 | Triazole Derivative and Use Thereof | F2R, HRH4, F2RL3 | ALOX15 1043/4885KDM4E 3414/4885LMNA 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.