Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | OXTR | P30559 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989824 | 0.92 | GPR6 (0.34) | LTB4RLTB4R2HCRTR2OXTRHCRTR1 | |
| SCHEMBL30989815 | 0.90 | TRPM8 (0.36) | HCRTR2HCRTR1PTGER4SCN9A | |
| SCHEMBL30989950 | 0.90 | GPR6 (0.37) | LTB4RLTB4R2HCRTR2OXTRHCRTR1 | |
| SCHEMBL30989774 | 0.90 | GPR6 (0.37) | LTB4RLTB4R2HCRTR2OXTRHCRTR1 | |
| SCHEMBL30989764 | 0.85 | SCN9A (0.33) | PTGER4PTGER2SCN9AGPR6 | |
| SCHEMBL30989839 | 0.83 | TRPM8 (0.37) | LTB4RLTB4R2HCRTR2HCRTR1GPR6 | |
| SCHEMBL30989838 | 0.81 | GPR6 (0.39) | HCRTR2HCRTR1GPR6KDM4C | |
| SCHEMBL30989859 | 0.81 | GPR6 (0.39) | HCRTR2HCRTR1GPR6KDM4C | |
| SCHEMBL30989905 | 0.80 | KDM4C (0.40) | OXTRAVPR1AGPR6KDM4CKDM6B | |
| SCHEMBL30989814 | 0.78 | MAPK1 (0.36) | HCRTR2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | claimed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | claimed |
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |